The most significant info for me are what are peoples real life experiences with them. "What has worked for you." You will find many people say they have been very effective for them for many years and have allowed them a quality of life they would have never had. Then you will find many people who say they have tried a bunch and they just don't work for them. Then you will find people like me who have had limited success. Some work very well, some not at all, and they usually poop out and I have to switch things up. My most recent experience is with Fetzima which straight up lifted me out of a very severe depression for the last five months and I have been able to live a normal happy healthy life. However I have to admit that in recent weeks I have been slipping and I don't know if it is losing effectiveness or not. I once started a thread for people to post on med success stories.

http://forums.psychcentral.com/psych...post-here.html

The former director of NIMH has said the current AD's and the chemical imbalance theory is a step in the right direction (not a myth) but it is far from the whole picture. That there has been too much focus on serotonin soup and they need to go in new directions and build on that knowledge.

One thing that turned me off about madinamerica was an article I read that said all psyche meds cause diabetes. Patently false. They also seem focused on law suits or at least some of the people affiliated with it.

I recently participated in a debate on facebook on these issues and the last post was by a psychiatrist that said he found all the evidence on both sides lacking and that the only important question is "What works for you." If you are scared of them don't take them but the goal still remains the successful treatment of the depression.