I take it daily, and have, for about 5 years. It has had minimal side effects for me, but does help with the mood regulation. [it also helps with migraines, if you happen to get those!] I take some anti-psychotics that cause weight gain, and Topomax is known for weight loss. My weight has stayed pretty consistent, so I credit it with helping me keep the anti-psychotic weight off. I've been pretty pleased with it. Hope this is helpful.