I've had no side effects, cognitive or otherwise. I can't say it's done much to stabilize my mood either though. I didn't feel better until the invega was added. I feel like the topamax might just be like candy but I'm afraid to mess with it in case it is doing something useful. But it definitely supressed my appetite, I will say that. I lost about ten pounds. I was surpised, usually I get the exact opposite side effects.