Hi there, I'm on week three of Lamictal and just went up to 100mg tonight. Right after I started taking it, my depression levels just suddenly tanked (I started keeping track of my moods using a free iPad app called "Optimism" when I got dx'd last month with BD), but it's unclear if that was because of starting Lamictal or just my depression suddenly just getting worse. I noticed my anxiety levels also increased significantly at the same time, but my pdoc said it was "possible but unlikely" that it was from the Lamictal. The therapeutic dose is 200mg, so I'm hoping I start to feel something better once I get up to that...I've been in a depressive episode more or less for a year and nine months now. A lot of people have said Lamictal works great for them, so I hope it does for you too. Good luck!