I have been taking Seroquel 200mg at bedtime for a few years. It has been extremely helpful for me.

Prior to the Seroquel I took Zyprexa but unfortunately it caused weight gain. What actually happened with the Zyprexa was I would get up at night and sort of 'sleep eat.' I'd often wake up with food wrappers and such in my bed but have no recollection of how they got there. So it wasn't actually the Zyprexa itself that caused the weight gain but rather a nasty side effect lead to the problem. When I discontinued the medication I began to lose the weight...12 lbs gone in the first month alone.

Here's a link to the Seroquel web site.