I am on Focalin XR and if I don't take it after a day of being on it, I feel like I have a hangover. My head pounds and I feel almost manic. That being said, when I was on a regular acting stimulant (Concerta), I would immediately feel off once the med wore off. It may just be that you are super sensitive to the medication. But I do understand the feeling out of control without the medication. It's like you really notice the contrast between being on it and not being on it.