I think it might be important at this juncture to remember that there are plenty of hormones that regulate the human body, not just the "female" or "male" type. Many chemicals are actually hormones, though we tend to forget that.

I tend to agree with the findings especially about the third major relapse probably requiring life long treatment. Further study might convince the naysayers also. Of course, Dr Wiley is not discussing fits of the "blues" but real major episodic depression, I think.