I have Epilepsy and i use that. I have been on it off and on for a few years. with no real problems. But it has not helped my depression. I use it for seziure control and it has at least worked well for that. So i'm going to start taking serquel.I wish it would help my depression. But it has not for me really.But i think i just need someone to talk to etc. Just went to a DR today about my depression problems. Went years ago but stopped going.