Thank you all for your posts. All are very helpful. I saw a pdoc who does TMS on Monday. He said it has only been approved/tested for people who have tried only one antidepressant that had not been effective. Has anybody else heard this? I am leaning toward "why bother" since I have been on more than 25 different antidepressants and multiple courses of E C T (also with severe short and long term memory and concentration consequences). Also, can anyone share what your cost would be? He quoted about $11,000+.