It's something that therapists and psychiatrists look for. When an adolescent or young adult (especially female( is clinically depressed or anxious that's not typical, and is a often sign that something might be off at home or elsewhere. When I was hospitalized at 12, all the staff initially assumed I was sexually abused. I wasn't, but I actually asked outright when my psychiatrist visited because I was curious (they really pushed the issue with me and my parents). She said I showed all the signs- withdrawn, drop in grades, depressed, sui, social anxiety, etc. She said the only big sign missing was substance abuse. Anyway, this is not something the general population notices, just people in the mental health field.