Well just call your Pdoc and then you will find out if she is willing to do med changes on the phone. Maybe just a bump up in seroquel would help .. Call and ask .. Do you think you can make it through the weekend safely? What are you doing for your ankle ? ice ? heat? elevated ? Physical pain can and will mimic and or cause depressive feelings.

I personally think waiting til October is too long. I would try like hell to be seen sooner .

Take care Keep posting here all you want and need to.