I have my "go too" depression med. I too have tried every med on the market without much success. I've had three back surgeries and was prescribed Vicodin for the pain. a remarkable thing happened when I was taking it, no depression.
I know it is an opiate and is addictive, but it cures (or masks) my depression for about 3-4 hours.
I occasionally take a half a pill when I know I am going to be in a social setting and even half a pill makes me feel much better. I am not advocating this method, just telling you what helps me for a few hours. It seems like even a brief break makes the rest of the day a little easier.