800 of seroquel knocks me out for sure! Glad it's working for you. Did you doctor prescribe that much or are you self-doctoring? The docs around here don't usually go so high on the dosage. They tried me on Seroquel mono therapy 900 mg at night when I was first diagnosed and I was a zombie and it wasn't helping my symptoms, neither the mania, depression, or psychosis. I complained, switched doctors, and found a high dose like that is an unusual practice, because of the risks.

Sleep can make a huge difference, I agree.