I had severe restless leg syndrome in my arms and back as well as legs. I twisted and jerked all night. I take manganese every morning now and that has stopped it. What a relief. I'd been to an orthomolecular psychiatrist years ago who recommended taking manganese if taking an antipsychotic to prevent tardive dyskinesia so I have done this. Recently I quit taking manganese for a month and all the jerking came back until I resumed taking it.