Crushing responses? Not unless keeping my mouth shut and worrying about what they said is to be considered a crushing response, lol.
But, I have been reading about how comedians and public speakers treat hecklers. I think I may take some of their advice.
Comedy Courses By The Sea » How to deal with hecklers.
How to Deal With Hecklers | eHow
Counterstrike - How to Deal With Hecklers
Most of the advice is about poise, and trying to determine how your audience, in general likes your "act". You don't want to lose the goodwill of your audience. If one is going to perform, then one must accept that there will be hecklers. It's part of what being a performer is all about. And one doesn't have to try to be funny when dealing with hecklers.
And I would truly like to develop a routine and actually get up on a stage and try it out.
I've got plenty of material from my YEC upbringing.