For me, I think I'm becoming more paranoid as I age, for one thing. Also, I have low-back problems. And, from time-to-time, I've had episodes when the muscles in that area became so strained that I couldn't get out of bed, except maybe to go (with excruciating pain) to the bathroom. (Fortunately I haven't had any of these kinds of episodes recently.)
Anyway, when I would have one of these episodes I would become extremely paranoid. I'd obsess about the possibility, either someone might break into the house & there would be nothing I could do, or the house might catch on fire & I couldn't get out. I do believe some of this paranoia has probably spilled over into my day-to-day life.