> In light of how SSRIs are often used. Read the 'skew the data' posts.

i'm not sure how that affects my point here. i'm not talking about the efficacy of SSRI's in every single person they are prescribed to (where GP's for example are often guilty of over-diagnosing). i'm talking about the efficacy of SSRI's in research studies where i'd assume they would be very careful indeed to pick out people who are in fact severely clinically depressed.

> I suppose neither you nor I work in primary care and see the efficacy of these meds in a lot of patients - do we?

i'm not sure how that relates either. clinical observations are unable to seperate the effect of the medication from the effect of placebo. that is the whole point in having double blind randomised controlled trials...