I think it has for me. Some days are so unbearable I have to miss work. Makes me think I will never advance in my career. I've always been ahead of my class, the youngest to graduate, the first with an early start in my career halfway through college. I was really on the fast track..but with the episodes getting harder and severe than the last, well, I feel like I am falling behind from the pack. It's hard to see the same people I started with at the assistant level now in director positions. The work I do is very high stress and to advance would undoubtably take all of my time and create more stress. I used to think I had no limits but this disorder has brought me down to reality and it sucks. I hate the fact that stress affects me more intensely than my colleagues. I just have to remind myself to do the best I can and to take care of myself.