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Hopefull said:
Also I have read that anti-depressants work better on vegetative symptoms such as sleeping problems, lack of energy etc. So, maybe some depressions are more psychological while some is both psychological and biological. Then some people have more of a biological issue with no or little psychological issues. If so, this might also cause problems with the studies. Depression can be different for different people.

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Yea is this a potential confound in some studies?

E.g. what were recruitment screening / criteria / sample structure?

For some reason I keep thinking about Masters students recruiting for 'depression-based' studies based on a 12-item BDI ...

:>

okay that was just a smartass comment but I think Hopefull raises an interesting point about sample structure.