Wellbutrin is one of those drugs that most people either do really well on or it messes them up. I'm one of the people it messed up---it made me manic and psychotic, and I apparently ran around threatening to kill people. I do not remember much of this, but I believe the people who told me that's what I did. In the end, I was diagnosed bipolar, not just because of the reaction to WB but because I'd had other wild times in my life interspersed with bouts of depression.