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The most comprehensive study I know of is the Star*D by NIMH that said 65% after six months. It emulated real world clinical practice. The numbers are all over the place though in many studies.
I too am very curious why they work for some and not others whatever the percentage.
I don't have any problem with the doctor and his approach to "functional medicine". Who can argue with a patient centered holistic approach. Who can argue with unbiased evidence based medicine. No scientist or researcher is totally unbiased. That is why we have the scientific method and peer reviewed publishing. Debates can go on for years before something is agreed upon fact. Actually medicine has been moving toward this for some time as far as patient centered holistic approach. I do have a problem with the title of the article since neither the article or the NEJM study says anything about "Why Antidepressants Don't Work", but that is the media today. A title to get you to read it.
My mental health clinic has a motto of "Patient Centered Recovery". You are expected to be an active participant in your treatment and recovery. To have a say in your treatment. You are required to have a medical doctor and to see them. They do all there own blood work in house and do the standard blood test to check thyroid, cholesterol, sugars, etc. They make recommendations on what to address with your medical doctor. My pdoc has full access to my medical doctors records. I can call a psyche nurse any time. I have a therapist. They have a ways to go in my opinion but not to bad for a clinic with tight budget constraints.