Hi, rustysterling, and welcome to Psych Central! I have taken Seroquel but not Brintillex. I wouldn't see any problem with taking them together, if that's something you're concerned about,

Alas, different drugs and drug combinations affect people differently. We just have to be patient while the doc experiments on us. I have been through many drugs and drug combos since I was diagnosed with bipolar years ago.

Maybe someone will come along who has taken both these drugs at the same time.