Did your Dr. try zyprexa, risperdal or even abilify first? Those are the first atypical anti-psychotic line of defenses for agitation. My last Dr. told me that seroquel is the least effective of the first two I mentioned above. They all have nasty side effects. I had a brief period where I was free of agitation when I first tried it and it was wonderful. I know how it feels being agitated on a daily basis. It's hell. Hang in there, man.