I believe very strongly in neuro plactisity. I think because I have read enough about it by reputable researchers and the experiments on primates with it. The success of stroke victims. I watched it work in my mom after a mild stroke. She regained all lost function. I have been trying for many years to apply it to my depression with meditation, CBT, the 12 steps of AA, visualization, etc., and it doesn't seem to work at all. Maybe depression is just to ingrained in me. I have never really had much faith that the current AD's would make permanent changes. Although there is some research that says they promote neuro trophic factors and dentrite growth.