Even within major depression there are differnt remedies, AD don't work for everyone and there are different types of therapies it is all individual and the best way to find out which is best for you is by consulting with a team.

Everyone here can say what worked for them but that's no guarantee that any one of those will work. But that is not a reason to despair because there is a unique treatment for you. Yes for most of us this illness is forever but there will be good times, it takes maintenance and a support system. There will be good times too.