My maternal grandfather was diagnosed as bipolar and was a classic case. My paternal grandfather was an alcoholic and committed suicide when my dad was 2, so I am guessing there was some illness there. My sister definitely has some depression and anger issues, but hasn't been diagnosed with anything. There are also some REALLY stable people in my family. I guess I just got lucky. I was diagnosed after my kids were born so I hope and pray they don't get it too. So far so good, but they are just 12 and 7.