I came off of Seroquel back in March because it caused me to become pre-diabetic and my cholesterol to sky rocket. We tried Latuda, my pdoc told me that Latuda was on the low end for causing these problems unlike Seroquel. I had problems with Latuda which would be a novel long if I explained it, in my case it didn't metabolize right in my body. I heard several people say that it changed their life. Unfortunately I had to go back on Seroquel. I hope everything works out for you.