Zyprexa was a good PRN for me, at least before I went on it full-time. I occasionally use Ativan (a benzo) when I'm anxious or can't sleep despite all the hardcore stuff I take at bedtime, but I have to ask my husband for it because it's locked up. (I OD'd on it a little over a year ago and can't trust myself with it.) Other people take the anti-psychotics Risperdal and Seroquel as PRNs. Everybody is different, so what works for someone else might not do it for you. It just takes experimentation.