My two Bipolar related PRN's are Clonazepam (Klonpin) 2mg and Olanzapine (Zyprexa) 5mg. I take the Clonazepam for anxiety and Olanzapine to deal with irritability, agitation and other mania/hypomania related things. I have found that during a hypo/manic episode I can take a ton of Clonazepam and it will not help me sleep. Only the Olanzapine works in that situation.