I have bipolar I and I feel like the dysphoric mania is mostly controlled now (I'm feeling less irritable, I sleep more - and more regularly, I'm not spending as compulsively as I had been). But can the depressive episodes occur alone if one has bipolar I with mixed states? Because I still feel the despair almost daily (without the energy, etc.) and I'm so withdrawn, isolated, and hopeless. Also, could Wellbutrin help if I'm already taking Lamictal and Latuda for mood stabilization? I do take Adderall as well, and I know Wellbutrin can increase the serum concentration of stimulants. If I cut back my dose of Adderall and asked my p-doc about adding Wellbutrin, can anybody tell me if they've been on this combo and if it worked for them? I just don't feel like I can continue to live with such debilitating depression and I need to find something that will help.

Thanks for any advice.