You're taking a lot of meds, this could be a side effect too... Can you talk to your doctor about maybe reducing or changing the meds?

Another thing could be nutrition (too many sweets can make me feel 'sugar blues' then, some people are more sensitive to this than others), or this time of year, the weather and lack of light... (it helps me to have lights on even during the day, and to go for a walk very day... even if the weather is 'sucky', I just have to force myself and then I feel better when I come back....)

Hope things get better!!