Neurogenesis = new growth of neurons and dendrites and new connections.
It has been shown for some time that chronically depressed patients have a smaller hippocampus. Shown in mice, primates and humans. Not caused by antidepressants but by depression. It is not known for sure whether a smaller hippocampus causes depression of if depression causes a smaller hippocampus.
Hippocampal volume loss in depression reflects glial loss -- ScienceDaily
The Johns Hopkins Psychiatry Newsletter
Depression, antidepressants, and the shrinking hippocampus
https://www.google.com/search?q=depr...Q&ved=0CDYQsAQ
Quite a few recent studies show that SSRI's and SSNRI's increase neurotrohpic growth factors and possibly the growth of new neurons in the hippocampus and cortex. This may explain why they work in the first place for many people and why it takes so long to work.
http://www.scientificamerican.com/ar...is-depression/
http://www.nature.com/npp/journal/v3...npp20132a.html
Fluoxetine-induced cortical adult neurogenesis. - PubMed - NCBI
Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor
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The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman
Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.
Male, 50
Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
Last edited by Altered Moment; Nov 30, 2014 at 05:16 PM.
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