Hi FuzzyBear!
I think I know how you feel. The drugs that work best on me are the ones I'm most allergic to. It's really hard to find a combination that helps, and I haven't had a real remission since my Prozac days back in the mid 90's. So I live with an underlying depression that I must fight year round. And since I'm bipolar, I can only take so high of a dose of any antidepressant. Right now I'm on three of them, and I think the only reason I'm not breaking out in hives is that I'm also on prednisone for another condition.
So know this, you are not alone.