Wellbutrin turned me into a psychotic, raging beyotch. It was so bad that the drug is now on my allergies list. I was running around at work throwing fits and threatening to kill a co-worker's abusive boyfriend, if that gives you any idea of how out-of-control I was. I stopped taking it because I was afraid I'd do something terrible, and then I turned into a weepy, anxious mess. This was just before I was diagnosed bipolar. I know WB works very well for most of those it doesn't send into full-blown mania, but I sure as hell will never touch it again.