I was diagnosed with a "General Mood Disorder" (whatever that means" that had a strong hormone-based problem. I was prescribed Topamax, 50mg, twice a day. I took it twice, once the night I got my prescription, and then the morning after.

The morning after, I woke up, felt pretty okay. A little nauseous, but I figured it was because I hadn't eaten. I ignored it and got myself to work. Once at work, all the nasty mean side effects kicked in.
I became dizzy, unable to focus, lost mental capacity (I'm a cashier and couldn't count above the number 13), I became incredibly suicidal, I lost motor functions.

That took about 48 hours to pass.

Now, granted, those were just my experiences.
I'm a smaller girl, I weigh 110lbs and I'm 5'2

My psych said it was unusual for anyone to have those side effects and have them so severly!