I have been treated for Recurrent Major Depression with Psychotic Features on and off for 30 yrs.

Over those years I have been on a multitude of different meds, with a multitude of different combinations. But all of that time I have been under the care of pdocs.

I currently take:
Effexor xr 600 mgs
Provigil 200 mgs
Wellbutrin 150 mgs
Remeron 15 mgs
Clozaril 200 mgs
and levoxyl after my thyroid was removed.

If you are under the care of a competent pdoc, please don't worry about the number of different meds you take, just enjoy the positive outcome.

Take care!