For what it's worth, 22 years ago I left my family and the place I grew up and have never looked back and have no regrets. Granted, I did this with my husband, so I was not alone, but I have always loved the adventure of it all. We have moved to 6 different states since then, always because of his work. We know what it is to live the American dream and to lose it all and it only made our lives richer even though now we are poorer.
There's a lot to be said for taking the plunge, so to speak. At the very least, it is never boring.
Good luck with your job interview!

WW