I can't say for sure it wrecks the metabolism but I can say I took it for 11 years and gained a total of 80lbs! Most of it was gained in the first few years. I didn't watch what I ate much but then after 3 years I tried to lose weight and couldn't! Then I tried again a few years later and still couldn't! I really couldn't lose weight on Citalopram until they added Ritain (which was added to help me stay awake not to lose weight). Then after they took me off Ritalin and Celexa I started dropping fairly easily without much effort. So I do believe it affects your metabolism but again I don't know if it wrecks it forever. I don't think anybody knows he answer to that unfortunately.

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