Hello tifferific: I've also been on quite a few antidepressants (& other stuff) over the years. For the past 2+ years, I've been on 120 mg. per day of Cymbalta. (This is the maximum recommended dosage.) It's not great, but it's the best med I've tried. Plus I have virtually no side effects.

The thing I wanted to say though is that my experience tells me the most I can hope to get from an antidepressant is that it will keep me from plunging so deep that I become a danger to myself. Beyond that, I have come to the conclusion it is up to me to manage my day-to-day and week-to-week fluctuations. My personal perspective is that we err when we think any med is going to make us feel well. To me, med's are simply one component of an overall plan to deal with my chronic mental health issues. My best wishes to you.