When in hospital for a depressive episode in Sept/Oct I was placed on Pristiq (desvenalflaxine) an antidepressant - 100mg. After about two weeks hypomania hit and lasted two months. My doc suggested I lower the Pristiq dose to 50mg to prevent me going into full-blown mania. I was going to but my mood has stabilised so I don't want to drop the dose in case I get depressed again. It is hard to find the right chemical balance.