I have the same problem as you. I have tried almost all the antidepressants out there. I am now on pristq & it is not working either. I do not know how much longer I can go on like this either. Hating everything, nothing brings me pleasure. I have my son & 2 grandsons coming to visit on Fri. & instead of looking forward to it I am dreading it. Just want to curl up in a ball under covers forever.