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Surely there are some psyc meds in here _Sky?
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From the list I posted, here are the psych drugs (that I recognize) affected by grapefruit at 3A4: Alprazolam, Amitriptyline, Buspirone, Carbamazepine, Chlorpromazine, Clomipramine, Clonazepam, Diazepam, Diltiazem, Haloperidol, Imipramine, Mirtazapine, Nefazodone, Sertraline, Temazepam, Tiagabine, Trazodone, Triazolam, Verapamil.
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My question was simply as an aside as I assumed the chemical process would be similar. Sorry for the distraction.
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Surely, it is the same issue. I used both psych and non-psych drugs to demonstrate just how powerful this effect can be. I reiterate that my concern was the general dismissal of this issue as being relevant to psych meds. The reference I used for Valium shows more than tripling of the the blood concentration from a single glass of grapefruit juice. 5 to 9-fold increase for Buspar. These are effects of which we are aware. The list I provided is not complete, by any stretch of the imagination.
Lar
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