I've been taking it for about 7-8 months now. I definitely had a decrease in sex drive at the beginning; it sort of balanced out after a while, even after increasing the dosage, but it still wasn't back at where it used to be. I'm now taking Wellbutrin along with the venlafaxine and I have found that that has increased my sex drive to more than it was to begin, if not even more than I want!