I don't think that's the case. This stuff takes a couple hours to kick in anyway, and I took it late last night, at 9pm. So I'm thinking taking it at 6pm would be a wiser mood. I'm suppose to take it with food anyway, so it makes sense to take it together with the rest of my meds after dinner. I'll give an update tomorrow. For the time being, it's one of those rare days where I have no side effects and I feel like myself.