I can definitely relate to this. When I first saw my psychiatrist, the first thing she asked was if I felt guilty about something--must have been something in my expression or demeanor that gave it away. Even now, after years of therapy, I have this nagging feeling of guilt running in the back of my mind that I constantly have to challenge. I also feel guilty if others are worried about me, which tends to lead to me isolating and not telling anyone whenever my bipolar/psychosis is bad.