You really must do it slowly, your doctor will advise you how to wean yourself off the meds by reducing the dosage gradually. Especially Effexor ! I came off it after a short period, thought I'd be fine...I thought I was going to die ! horrible shocks in your head, like your brain is spinning in your skull ! Some meds are safer to stop abruptly than others. Don't try to do it alone, it's dangerous. Good luck !