I am female and have had both male and female T's. About six months into therapy I accidentally discovered that my current male T is a female to male transgender. It was surprising to me and it affected our relationship, mostly because I had limited awareness of the transgender community. I joked afterwards that I wouldn't have been so shy about discussing my PMS if I had known! I imagine he has a better understanding of the female experience than most men, but I haven't really noticed a difference. I'm just thankful that he is a good T.