Hey Skinned,
I just saw your post also let me tell you my experiences. I am not sure it will help or not. I have been on Pristiq for about year and 8 months. When I first started the drug I was only on 50mg and truly thought it was a wonder drug because I felt so good actually stopped therapy for 4 months (jumped the gun on that). Then the effects started to wear off and started getting back to my old self. Next I bumped up to 100mg like you it took a little of the depression and anxiety away. Not great but better. Just so you know I am on other drugs also to help with everything. About a month ago I started another drug called Lamcital it has helped but did not get off Pristiq you can see my full list in my signature. I really did not want to be taking another drug but I think it is the nature of the beast (mental health issues). The one thing I do know is make sure if you do get off that you do it with a professional guidance because getting off any mental health medication abruptly can very dangerous (likes of side effects) Take care of yourself...