I was hoping I could get some insights from some of the others here. I've been dealing with depression my entire life, though I wasn't diagnosed until 2001. Since then I've been on Prozac and have done pretty well. Then, in early 2010 I had the most severe episode to date; in addition to the crippling feelings of worthlessness, I experienced several months of extreme anx... (if any) have worked for you? This seems to be getting worse each year, and I'm losing the energy to cope.