I've been on lamictal since I was diagnosed about eight years ago. Over the years I noticed my photographic memory declined a little bit. Back in August my pdoc put me on Topamax (topiramate) for weight loss because I had to go back on Seroquel. I started to notice major cognitive issues, mainly memory and focus. I talked to my pdoc about a month ago and he said it's because both Lamictal and Topamax are anti-convulsants and they have these affects on cognition. I definitely wanted to stay on my Lamictal, 400mg, so we have been weaning me off of the Topamax. I was on 100mg and I have been down to 50mg for three weeks and I have already noticed a major difference. My photographic memory is coming back. I'm not repeatedly having the same conversations with my husband. I feel so much better. This is just my experience with the two meds your on.